Genentech Receives First ADC Approval

Kadcyla approved for HER2-positive metastatic breast cancer

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Genentech has received FDA approval for Kadcyla (ado-trastuzumab emtansine or T-DM1) for the treatment of HER2-positive metastatic breast cancer (mBC) in patients that have received prior Herceptin and chemotherapy treatment. Kadcyla, an antibody-drug conjugate (ADC), is a new kind of targeted cancer medicine that can attach to certain types of cancer cells and deliver chemotherapy directly to them. Kadcyla is the first FDA-approved ADC for treating HER2-positive mBC.   “Kadcyla is an antibody-d...

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